Please enable JavaScript.
Coggle requires JavaScript to display documents.
Chronic Myeloid Leukemia (CML) - Coggle Diagram
Chronic Myeloid Leukemia (CML)
Definition
A type of cancer that affects the blood and bone marrow, characterized by the overproduction of abnormal white blood cells
Causes
A specific genetic mutation (BCR-ABL) in the bone marrow cells.
Symptoms
Swollen lymph nodes
Fever
Bleeding and brusing
Night sweats
Weight loss
Joint pain
Fatigue
Diagnosis
Bone marrow biopsy
CBC
Cytogenetic analysis
Molecular Testing
Prognosis
Long term survival
Generally favorable
Treatment
Stem cell or bone marrow transplant
Chemotherapy
Tyrosine Kinase Inhibitor (TKIs) (Imatinib & Dasatinib)
Complications
Blast crisis
Secondary cancers