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Inflammation - Coggle Diagram

- - - - Vasodilation
      - Increased Vascular Permeability
    - - Cellular recruitment
        
        Extravasation
        
        Sequence of events in Leukocyte migration from vessel lumen to interstitial tissue
        
        Margination
        
        The fast moving small red cells push neutrophils to the periphery where they accumulate along the endothelial surface
        
        Rolling
        
        Leukocyte tumbles along the endothelial surface undergoing weak and transient adhesion
        
        This is done by attaching to different types of selectins
        P-selectin: on endothelium and platelets
        E-selectin: on endothelial cells
        L-selectin: on leukocytes
        
        Adhesion
        
        Firm adhesion to the endothelial cells is achieved when the integrins on the neutrophils that were previously inactive get activated as a result of cell injury
        
        1 more item...
        
        Transmigration
        
        2 more items...
      - Activation of Leukocytes (neutrophils)