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Opioid Drugs - Coggle Diagram
Opioid Drugs
Relative Contraindications
Severe Asthma
Respiratory insufficiency
Morbid Obesity
Pregnancy
Known Drug Allergy
Paralytic Ileus
COPD
Adverse Effects
Decreased Rate and Depth of Respiration
Respiratory Depression
In overdose can cause respiratory failure
Death
Slow Breathing
Decreased GI Motility
Abdominal Pain
Nausea
Vomiting
Constipation
Altered Mental Status
Sedation & Mental Clouding
CNS Depression
Drowsiness
Confusion
Dizziness
Dependence & Tolerance
Chronic use can cause physical and psychological dependence
Withdrawal symptoms
Requires increasing doses
Histamine Release
Itching
Vasodilation
Orthostatic Hypotension
Flushing
Urinary System
Urinary Retention
Therapeutic Effects
Pain Relief
Anxiety Reduction
Cough Supression
Antidiarrheal
Common Uses
Pain Relief
Chronic Pain
Severe Acute Pain
Cough Supression
Suppress cough reflex
Useful for non productive cough
Sedation & Anxiety
Relaxation, Calmness, Drowsyness
Antidiarrheral
Slow GI Motility
Mechanism of Action
Agonists
Bind Opioid Receptors
Activate Receptors to Reduce Pain
Representative Drugs
Fentanyl
Oxycodone Hydrochloride
Hydromorphone
Morphine Sulfate
Codeine Sulfate
Meperidine Hydrochloride
Agonist-Antagonists
Partial Activation of Receptors
Mixed Effect on Pain Relief
Representative Drugs
Nalbuphine
Pentazocine
Antagonists
Block Opioid Receptors
Reverse Opioid Effects
Representative Drugs
Naloxone