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Dendritic Cells, Plasmacytoid DCs, cDC1, cDC2 - Coggle Diagram
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cDC1
Identification
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Lack of Expression of
monocyte and cDC2
markers such as CD14, CD11b
and SIRPa
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cDC2
Identification
Express
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CD11b, CD11c, CD13 and CD33
CLEC10A (CD301a), VEGFA and FCGR2A (CD32A)
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Transcription Factors
GATA2, PU.1, GFI1, ID2,
ZEB2, RELB, IRF4, NOTCH2 and KLF4
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Function
Presentation of antigens
Wide range of lectins, TLRs, NOD-like receptors and RIG-I-like receptors
Location
human blood, tissues and lymphoid organs