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Muscles, contraction cycle - Coggle Diagram

- - - - myosin head binds to toponin on acting filament
      - crossbridge form/reform
        
        thin filament pulled to centre of sarcomere
      - sarcomere shorten - muscle cell shortens
        
        many shorten together = muscle contract
  - - - other energy
        
        glucose --> glucogen
      - ATP + creatine = creatine phosphate
        
        via creatine kinase
        
        maker of muscle damage
      - Makes more ATP
        
        cannot be stored
    - - O2 still avail
      - sufficient ATP
      - fatigue delayed
    - - Anaerobic conditions
      - little ATP
        
        P from CP used to make ATP
      - faster muscle fatigue
    - - energy reserve in muscle
      - normal blood supply, O2 levels, blood pH
    - - hours - days
      - lactic acid - pyruvic acid - ATP or glycogen
      - more O2 needed
    - - triggered by mechanical signals
      - increase in myofibrils
      - more/bigger mitochondria
      - more blood vessels
- - - - lenticular or spindle shaped
      - single central nucleus
- - - - immunosuppressants
      - thymectomy
      - plasmapheresis