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Hashimoto's Thyroiditis - Coggle Diagram
Hashimoto's Thyroiditis
Treatment
Levothyroxine
Taken before breakfast and caffeine
Dosage according to patient weight
Lifestyle modifications
Diet
Anti-inflammatory diet
Elimination diet
Exercise
Yoga, walking
Avoid extreme exercise
Stress management
Pathophysiology
Autoimmune response
Antibody production
Thyroglobulin (Tg)
Thyroid peroxidase (TPO)
Thyroid stimulating hormone (TSH)
Lymphocytic infiltration
Thyroid specific B and T cells
Follicular destruction
Hashitoxicosis in the earlier stages
Thyroid dysfunction
Hypothyroidism
Goiter formation
Caused by genetic susceptibility and environmental factors
Precipitating factors: Stress, infection, female sex, pregnancy
Phenotypes
goitrous autoimmune thyroiditis
Atrophic autoimmune thyroiditis
Stages
Genetic predisposition
Immune cell infiltration
Subclinical Hypothyroidism
Overt hypothyroidism
Additional autoimmune disease
Thyroid atrophy
Multisystem Alterations
Cardiovascular
Raynaud's Phenomenon
High cholesterol
Atherosclerosis
Hypertension
Reproductive
Menstrual irregularities
infertility
complications during pregnancy
Nervous system
Peripheral Neuropathy
Musculoskeletal system
Joint pain
Muscle cramps
stiffness
Integumentary system
Skin
Uriticaria
dry, coarse, pale
Myxedema
Hair loss
Diagnosis
TPO
May be elevated before symptoms
Family history of autoimmune thyroid disease
TSH
Clinical Manifestations
Fatigue and weakness
Cold intolerance
Constipation
Weight gain
Depression and cognitive impairment