Axillary LN dissection

no suspicious LN at diagnosis

Clinically suspicious of LN at diagnosis

consider omitting SLN excision

SLN mapping and excision

SLN not identified

SLN negative

SLN positive

Breast conserving surgery

Mastectomy

no further Axillary surgery indicated

consider Axillary dissection of Level I / II region

criteria

  • cT1-T2, cN0
  • no neoadjuvant C/T
  • 1 to 2 positive SLNs
  • WBRT planned

No

ALND over Level I / II

Yes

no ALND indicated

micrometastasis in SLN

no ALND indicated

Criteria

  • cT1-T2, cN0
  • No neoadjuvant
  • 1 to 2 positive SLN
  • Adjuvant RT planned

No

ALND over Level I / II

Yes

consider no further ALND

micrometastasis in SLN

no ALND indication

sono-guide FNA or core Bx

negative

positive

≥ 3 positive suspicious LN

SLN mapping and excision 同上流程

Neoadjuvant therapy

≤ 2 positive LN

SLN mapping and excision 同上流程

ALND over level I / II

clinically nodes negative after neoadjuvant

meet the criteria below:

  • marking biopsied LN
  • dual tracer
  • removing ≥ 3 SLN and all are negative

No

ALND over Level I / II

Yes

no ALND indication

residual disease

ALND over Level I / II

Neoadjuvant C/T was given

SLN mapping and excision 同上流程

for cT1N0, ER strong, HER2 negative, post-menopausal, and plan to receive breast conserving surgery and WBRT