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Assistant Prof. 陳緯 image - Coggle Diagram
Assistant Prof. 陳緯
Cancer Therapy
Sn nano particles (2D material)
Graphene-like structure
表面修飾biocompatible substrate (drug)
SonoDynamic Therapy (SDT)
Thermostability
Light -> electron hole exist -> ROS formation -> kill tumor cell!
M2 -> M1 macrophage
Cell died!
SnSNPs
Photothermal -> Stroma barrier damage
Fe ion
Tumor inhibition effect
Tumor vaccine
PROTAC
Atherosclerosis (動脈粥狀硬化)
Formation
Smoking、高油高鹽飲食
Attract monocyte -> foam cell -> 內皮cell die -> 栓塞formation > 血肌梗塞、中風
Therapy
LDL-C drug
may cause 糖尿病
e.g. PCSK9 inhibitor
anti-inflammatory drug
may raise the possibility of 細菌感染
Monocyte Inhibitor
阻止monocyte吸引至血管內皮
抑制monocyte過度繁殖
促進macrophage to clean up thode dead cells
drug抑制血管產生炎症因子
drug清除monocyte
monocyte有效排除cholestrol
