Tourette Syndrome

Tics

Sudden repetitive sterotyped movements, simple or complex

Seen more in males, can wax and wane, suppressible, and premonitory urges

Natural History

Onset between 5-6, worse between 10-12 years of age, and most patients have spontaneous remission/improvement over time

1/3rds rule

1/3 resolve, 1/3 improve, 1/3 remain the same

Comorbidities

ADHD, OCD, Anxiety, Leraning disability, pervasive developmental disroders, ODD, Sleep problems

May be more significant than tics, treating may reduce anxiety/stress

Approach

Education (Explanation, nautral hsitory, dispell myths)

Medications

1st line: Alpha Agonists (Clonidine, Guanfancine, Behavioural Treatment)

2nd Line: Atypical antipsychotics, antipsychotics, botox

behavioural Treatment

Habit reversal training (Tic Awareness, competing response training)

Tic Awareness (Self-monitoring of tics, focus on premonitory urge)

Competing response treatment (Engage in voluntary behaviour incompatible with tic)