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GROWTH HORMONE RELATED DRUGS, Increased GH, Decreased GH, OR, Use:-…
GROWTH HORMONE RELATED DRUGS
Acromegaly
Somatostatin Analogues
S/E
Hypothyroidism & Gall stones
Oct
reotide
Lan
reotide
Pas
ireotide
DOC
Vipoma
Glucagonoma
Secretory Diarrohea
Acromegaly
GH Receptor Blocker
Pegvisomant
Use:-
Resistant Acromegaly
S/E:-
Pituitary Adenoma
SERM (Selective Estrogen Receptor Modulators)
Inhibit IGF-1 Level
Tamoxifen
Dwarfism
GHRH Analogues
Sermo
relin
Macimo
relin
Tesamo
relin
Use:-
to determine whether the Dwarfism is of
Pituitary origin
Hypothalamic origin
GH Analogues
Somatrem
Somatropin
Somapacitan
DOC
for Dwarfism
S/E:-
CTS (Carpel Tunnel Syndrome)
Hyperglycemia
Leukemia
DM
IGF1 Analogues
Mecarsermin
Mecarsermin Rinfabate (IGF1 bound to IGFBP-3)
Increased GH
Decreased GH
OR
Use:- Acromegaly with breast cancer