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lieky ovplyvnujuce zrazanie krvi - Coggle Diagram

- - - - inhibitory COX
        
        ASA
        
        indobufen
      - blokatory TxA2-R
        
        ridogrel
        
        nidogrel
      - inhibitory tromboxan syntezy
    - - tienopyridiny
        
        klopidogrel
        
        tiklopidin
        
        vyrazne NU= pancytopenia, atd
        
        prodrugy, p.o, cez CYP, irreverzibilne, eliminacia renalna aj fekalna, ucinok viac dni
        NU= krvacanie
        
        prasugrel
      - non-tienopyridiny
        
        TIKAgrelor
        
        aktivne, nie cez CYP, reverzibilne, NU= krvacanie, dyspnoe, bradykardia, alergie
        
        KANgrelor
        
        i.v, renalna eliminacia
    - - naftidrofuryl
    - - abciximab
      - tirofiban
      - eptifibatid
    - - dipyridamol
      - cilostazol
  - - - hepariny
        
        nefrakciovany
        
        nizkomolekularny
        
        dalteparin
        
        enoxaparin
        
        nadroparin
        
        bemiparin
        
        pentasacharidy
        
        fondaparinux
        
        ine
        
        sulodexid
        
        heparinoid
      - priame inhibitory trombinu
        
        hirudin
        
        hirudinove analogy
        
        bivalirudin
        
        lepirudin
    - - priame inhibitory Xa
        
        apixaban
        
        rivaroxaban
      - priamy inhibitor trombinu
        
        argatroban (p.o.)
      - warfarin
  - - - streptokinaza
      - urokinaza
      - anistreplaza
    - - alteplaza
    - - reteplaza
      - tenektoplaza
      - stafylokinaza