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gout treatment, كولاجسين - Coggle Diagram
gout treatment
chronic gout
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Uricosuric drug
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probenecid
blocks the tubular secretion of penicillin and is sometimes used to increase levels of β-lactam antibiotics
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uricase enzyme
Pegloticase
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indicated for patients with gout who fail treatment with standard therapies such as xanthine oxidase
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Initiation of urate-lowering therapy can precipitate an acute gout attack due to rapid changes in serum urate concentrations. Medications for the prevention of an acute gout attack (low-dose colchicine, NSAIDs, or corticosteroids) should be initiated with urate-lowering therapy and continued for at
least 6 months
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Most therapeutic strategies for gout involve lowering the uric acid level below the saturation point (6 mg/dL), thus preventing
the deposition of urate crystals
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