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Altered Hormonal and Metabolic Function, Damage to Endocrine Glands,…
Altered Hormonal and Metabolic Function
Hyperthyroidism
DIAGNOSTICS
Serum TSH screening
PE, family and past history, presentation
Free thyroxine measurement
MANIFESTATIONS
Exophthalmos
Heat intolerance
Tremors
TREATMENT
Thyroid gland ablation
Oral thyroid supplementation
Radioactive iodine
Addison Disease
DIAGNOSTICS
Corticosteroid levels
Lab analysis
Clinical presentation
MANIFESTATIONS
Skin melanocytes
Hypotension, Hypoglycemia, Hyponatremia
Personality changes
TREATMENT
Isotonic IV
Hormone replacement
Inappropriate ADH Secretion
DIAGNOSTICS
Serum sodium
Plasma osmality
Urine volume and concentration
MANIFESTATIONS
Confusion
Anorexia
Hyponatremia
TREATMENT
Fluid restriction
Hypertonic or Isotonic IV
Hypothyroidism
DIAGNOSTICS
Elevated TSH
Lowered T3 and T4
MANIFESTATIONS
Myxedema
Cold intolerance
Goiter
TREATMENT
Hormone replacement
Levothyroxine
Symptom management
Diabetes Insipidus
DIAGNOSTICS
PE findings
Patient history
Lab measurements
MANIFESTATIONS
Polydipsia
Nocturia
Polyuria
TREATMENT
Desmopressin
Vasopressin
Hydration
Cushing Syndrome
DIAGNOSTICS
Elevated cortisol
24-hour urine
Imaging studies
MANIFESTATIONS
Hirsutism
Euphoria, psychosis
Central obesity
Moon Face
TREATMENT
Corticosteroids
Surgery
Radiation Therapy
Damage to Endocrine Glands
Damage to Metabolism and Elimination Mechanism
Damage to Hypothalamic-Pituitary Axis
Damage to Cell Receptors
Damage to Endocrine Glands
Damage to Feedback Mechanisms