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Altered hormone processes, Cushing syndrome, Adison's disease - Coggle…
Altered hormone processes
Syndrome of Inappropriate Antidiuretic Hormone Secretion
Tumor
excessive production and release of ADH
water retention
intracellular accumulation
altered cell function
exess cell fluid
increase body water concentration
diluted sodium concentration
clinical manifestations
Hyponatremia
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diagnostic criteria
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ectopic ADH
Diabates Insipidus
Ingestion of large volumes of fluid and decreasing ADH levels
Ineffective posterior pituitary secretion
Nephrogenic DI
Insufficient hypothalamic ADH production
Insufficient ADH
Inability to concentrate water
Inability to retain water
Clinical manifestations
polyuria
polydipsia
Serum hypermosality
shock
Dehydration
diagnostic criteria
lab test results
low urine specific gravity or low urine osmality
physical exam
dehydration
bladder enlargement
patient history
head trauma
bran surgery
treatment
antidiuretics
hydration
Hyperthyroidism
graves disease
IgG antibodies blind to TSH receptor cells on thyrocytes
thyrotoxicosis
hyperplasia
clinical manifestion
goiter
diagnostic criteria
lab tests
suppressed serum TSH levels
patient history
family history of autoimmune disease
physical exam
enlarged thyroid
protrusion of eyes
treatment
antithyroid medications
beta blockers
radioactive iodine therapy
hypotension
thyrotoxic crisis
exophthalmos
medications with iodine
pituitary adenoma excess production of TSH
Hypothyroidism
acquired
Removal of or radiation to thyroid
iodine deficency
medications
autoimmnity
blocks TSH or TSH receptors without activating thyroid gland.
hashimoto thyroiditis
clinical manifestations
goilter
myxedema
diagnostic criteria
decreased serum thyroid hormone
elevated TSH levels
treatment
monitoring
hormone replacement therapy
congenial
lack of thyroid secretion and production
congenital hypothyroidism
impaired growth
intellectual disability
exogenous
pituitary gland tumors that stimulate excess ACTH production
overstimulates adrenal cortex
hyperplasia
excess cortisol production
adrenal gland tumors that stimulate excess cortisol production
ectopic proudction of ACTH or CRH from tumor at a distant site
endogenous
long term corticosteroid medications
suppression of cortisol production
clinical manifestations
protein degradation
exremeity weakness and muscle wasting
obesity
moon face
buffalo bump
striae
glucose intolerence
diabetes mellitus
diagnostic criteria
urine collection
measure elevation in cortisol excretion.
image studies
locate tumors that may secrete excess ACTH.
treatment
corticosteriods
remove cause of tumor
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autoimmuine destruction of layers of adrenal cortex
insufficient adrenal cortex production of aldosterone and cortisol
tumors
drugs that block corticosteriod synthesis
adrenal bland granulomas
inability to adrenal glands to produce.
mineralcorticoids
androgens
glucocorticoids
ACTH elevate to increase these secretions
stimulate skin melanocytes
clinical manifestations
hyperpigmentation
mucous membrane
skin
diagnostic criteria
lab analysis
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Cushing syndrome
Adison's disease