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Constipation + Diarrhea, Salts, Loperamide, Irratant/Stimulant Laxatives…
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Loperamide
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Overdose: paralytic ileus, CNS depression Caution in IBD (toxic megacolon)
Toxic Materials •Microorganisms (salmonella, E.coli)
•Antibiotic associated
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Lubiprostone
no tolerance or dependency,no drug interaction
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Castor Oil - From the Castor Bean •Senna - Plant derivative
•Bisacodyl (Available as supp.enteric coated tabact directly on nerve
fiber in the mucosa of colon) *Lubiprostone stimulates chloride channels
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