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"I'm So Pale" - Coggle Diagram

- - - - properties
        
        Insoluble
        
        From Vegetables
      - Ferrous reductase
    - - properties
        
        Soluble
        
        From meat
      - Ferrous oxidase
  - - - duodenum
        
        why?
        
        as it is the most acidic part small intestine
    - - Enters enterocytes through
        
        DMT1
    - - Enters enterocytes through
        
        HCP1
  - - - Ferroportin 1
        
        transported by binding to
        
        apotransferrin forming transferrin
  - - - L-type in
        
        Liver
      - S-type in
        
        Heart
- - - - dietary intake and absorption of iron
  - - - Measures the capacity of transferrin to bind iron which is high in iron deficiency
  - - - iron deficiency
    - - iron overload or infection
- - - - Increase iron intake via food
        
        Oral supplementation
        
        Parenteral (if needed)
        
        Blood transfusion (if needed)
        
        when to use?
        
        Patients who can not tolerate oral iron
        
        Patients that reduced gastric acidity
        
        Absorption
        
        The lower the iron stores the more iron is absorbed
      - example
        
        Stop cow milk consumption for infants
        
        Stop medications interfering with iron absorption
        
        Treat diseases like inflammatory bowl disease
        
        Stop blood loss
- - - - what is it?
        
        Proportion of all tests preformed that give the correct value
    - - what is it?
        
        The ability of the test to produce the same results when repeated on the same patient
  - - - what is it?
        
        A test should be conducted on a broad spectrum of patients
    - - what is it
        
        Not too small and too large
  - - - what is it?
        
        the probability that an individual with a disease will test positive
    - - what is it?
        
        the probability that an individual without the disease will test negative
  - - - ROC
    - - How good the test is, greater AUC = better test