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Immunosuppressants, Monoclonal antibodies (Mabs), Calcineurin inhibitors,…

- - - - Lysis and blocking B-cell activation
        
        XX antibody-forming plasma cells
- - - - affects auto reactive B
        
        It is approved for systemic lupus erythematosus
        
        several warnings regarding serious and fatal infections in patients receiving
        concurrent immunosuppressive agents
        
        Live vaccines are relatively contraindicated