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Diseases that cause liver lesions - Coggle Diagram
Diseases that cause liver lesions
Viruses
multifocal necrosis
Adenoviruses (canine adenovirus)
Influenza
Herpesvirus in neonates
Lymphohistiocystic hepatitis
Porcine circovirus 2
Granulomatous hepatitis
FIP
Rabbit hemorrhagic disease (calicivirus)
Equine serum hepatitis -> dishrag liver
Bacterial
Listeria monocytogenes
Campylobacter fetus
Mannhemia haemolytica
Histophilus somni
Actinobacillus spp
Salmonella
Mycobacteria
Fusobacterium necrophorum
secondary to omphalitis or rumenitis
cause coagluative necrosis (cheesy leisons)
Leptospirosis
acute jaundice, cholestasis and renal failure
Clostridium novyi Type B (Black head disease)
spores are ingested on pasture -> live in kupffer cells -> necrosis (often due to liver flukes) causes anaerobic conditions which activate them -> spores produce necrotizing toxin -> congested subcutaneous vessels (which turns black)
Clostridium hemolyticum (similar to blackhead diseease)
Clostridium piliforme (Tyzzer's disease)
causes multifocal necrosis
Parasites
Migrating larvae
Ascaris suum (milk spotted liver) in pigs
Fasciola hepatica
affects ruminants
larvae migrate through liver and can cause fatal anemia and spark blackhead disease due to the necrosis they cause (ignite clostridium novyi Type B spores)
adults live in BILE DUCTS -> dilation and fibrosis of the ducts
Fasciola magna
lives in liver PARENCHYMA
local in the deer population here
in cows, it migrates briefly but no connection to bile ducts
if it gets into sheep, it never stops migrating = very deadly