Year 10 Mock revision Biology

Cells, organisation and microscopy

Cells are the basic building blocks of all organisms.

A tissue is a group of cells with a similar structure and function

Plant and animal cells are eukaryotic

They have a cell membrane, cytoplasm and genetic material (DNA) enclosed in a nucleus

Animal sub cellular structures

Nucleus-controls activities of the cell

Cytoplasm - where most chemical reactions take place

Cell membrane- controls the passage of substances into and out of the cell. It also contains receptor molecules.

Mitochondria - where aerobic respiration takes place

Ribosomes - where protein synthesis occurs.

Plant sub cellular structures

Chloroplasts absorb light (using chlorophyll) to make food by photosynthesis

Permanent vacuole - filled with cell sap

Cell wall - made of cellulose and strengthens the cell

bacteria cells are prokaryotic and much smaller in comparison

They have cytoplasm and a cell membrane surrounded by a cell wall

The genetic material is not enclosed by a nucleus. It is a single DNA loop and there may be one or more small rings of DNA plasmids

Specialised cells

Sperm cells are specialised for reproduction

nerve cells are specialised for rapid signalling

muscle cells are specialised for contraction

Long tail and streamlined head to help it swim

Lots of mitochondria to provide energy

Carries enzymes to digest the membrane of the egg

They are long to cover more distance

branched connections at their ends to connect to other nerve cells and form a network throughout the body.

They are long so they have space to contract

They have lots of mitochondria to generate energy for contraction

root hair cells are specialised for absorbing water and minerals

xylem and phloem cells transport food and water around plant.

The cells are joined end to end to form tubes

xylem are hollow at the centre

phloem have few subcellular structures so that stuff can flow through them

they have a big surface area to maximize opportunity for absorption of water and mineral ions

Respiration

Respiration is exothermic because it transfers energy to the environment

The energy transferred supplies all the energy needed for living processes.

Respiration in cells can take place aerobically (using oxygen) or anaerobically (without oxygen) to transfer energy.

Aerobic respiration

glucose + oxygen → carbon dioxide + water + energy release

C6H12O6 + O2 = CO2 + H2O + energy

Anaerobic respiration

As the oxidation of glucose is incomplete in anaerobic respiration much less energy is transferred than in aerobic respiration.


The heart rate, breathing rate and breath volume increase during exercise to supply the muscles with more oxygenated blood. This enables increased cellular respiration so more energy is transferred to meet the demands of the muscle cells.


If insufficient oxygen is supplied, anaerobic respiration takes place in muscles. The incomplete oxidation of glucose causes a build-up of lactic acid and creates an oxygen debt. During long periods of vigorous activity muscles become fatigued and stop contracting efficiently.


Comparing aerobic and anaerobic respiration

Aerobic

Anaerobic

Only occurs if there is not enough oxygen

produces lactic acid

Only requires glucose

Creates oxygen debt

Does not transfer as much energy as aerobic respiration because the glucose isn't oxidised fully

creates muscle fatigue

requires oxygen

provides more energy compared to anaerobic respiration and is more efficient

occurs all the time in plants and animals

occurs inside mitochondrea

Produces water and carbon dioxide as waste products

Circulatory system

The heart is an organ that pumps blood around the body in a double circulatory system. (Heart to lungs to heart; heart to rest of body to heart)


Left ventricle

right ventricle

left atrium

right atrium

The left ventricle has a thicker wall with more muscle to generate a higher pressure to pump blood a longer distance to the rest of the body

Blood vessels

Arteries

veins

cappilaries

carries oxygenated blood away from the heart

Thick walls as the blood is under pressure

elastic fibers and muscles even out the pressure in the artery

Small lumen, making the blood high pressure so it can be distributed around the body quickly

form a network of tiny vessels linking the arteries and veins

Narrow with thin walls so that oxygen and glucose can diffuse easily

One cell thick

Narrow lumen

carries low oxygenated blood away from organs towards the heart

Thin walls and large lumen to make a low pressure

Valves to stop the blood at low pressure flowing back

The natural resting heart rate is controlled by a group of cells located in the right atrium that act as a pacemaker.


Red blood cells contain haemoglobin which binds to oxygen to transport it from the lungs to the tissues.


In coronary heart disease layers of fatty material build up inside the coronary arteries, narrowing them, reducing the flow of blood and resulting in a lack of oxygen to the heart cells.


Stents are used to keep the coronary arteries open.

Statins are widely used to reduce blood cholesterol levels which slow down the rate of fatty material deposit.

In the case of heart failure a donor heart, or heart and lungs can be transplanted. Artificial hearts are occasionally used to keep patients alive whilst waiting for a heart transplant, or to allow the heart to rest as an aid to recovery


Plants

carbon dioxide + water →(light) glucose + oxygen

CO2 + H2O = (light) C6H12O6 + O2

Photosynthesis is an endothermic reaction in which energy is transferred from the environment to the chloroplasts by light.

Rate of photosynthesis

Light

If there is more light, more photosynthesis can take place

Temperature

As temperature increases, the rate of photosynthesis increases

Photosynthesis is controlled by enzymes which denature around 40-50 degrees. Therefore, if the temperature gets too high, the enzymes denature and the rate of photosynthesis falls

Carbon dioxide concentration

Increasing the CO2 concentration increases the rate of photosynthesis

On a sunny day, CO2 concentration is usually the limiting factor for photosynthesis.

The CO2 concentrations around a plant rise at night because in the dark, plants respire but don't phtotosynthesize

Communicable diseases

Pathogens are microorganisms that can cause infectious diseases

Viruses

Bacteria

Protists

Fungi

Cells with no nucleus, can produce toxins that damage tissues, treated with antibiotics

Only reproduce inside host cells, no nucleus (viruses are not made of cells)

Treated with antifungals, cells have a nucleus

Cannot be classed as an animal, plant or fungus, cells have a nucleus

Pathogens may infect plants or animals and can be spread by direct contact, water or air.


Malaria

Symptoms of recurrent episodes of fever, which can be fatal. Spread is controlled by preventing the mosquito vectors from breeding and by using mosquito nets to avoid being bitten.

Non-Communicable diseases

Traditionally drugs were extracted from plants and microorganisms.

The heart drug digitalis originates from foxgloves.

The painkiller aspirin originates from willow.

Penicillin was discovered by Alexander Fleming from the Penicillium mould.

Results of testing and trials are published only after scrutiny by peer review to help prevent false claims.

Different types of disease may interact:

Defects in the immune system that means an individual is more likely to suffer from infectious diseases

Viruses living in cells can be triggers for cancers

Immune reactions initially caused by a pathogen can trigger allergies such as skin rashes and asthma.

Severe physical ill health can lead to depression and other mental illness.

Monoclonal antibodies are specific to one binding site on one protein antigen. They can therefore target a specific chemical or type of cell within the body.

Mouse lymphocytes are stimulated to produce a specific antibody

Lymphocytes combined with a tumour cell to form hybridoma cells.

Hybridoma cells both divide and make the antibody.

Single hybridoma cells are cloned to produce many identical cells that all produce the same specific antibody.

A large amount of the antibody can be collected and purified.

image

Uses of Monoclonal antibodies

Diagnosis: in pregnancy tests a monoclonal antibody binds to the hormone hCG produced by the embryo.

In laboratories: monoclonal antibodies are used to measure the levels of hormones and other chemicals in blood, or to detect pathogens.

In research: to locate or identify specific molecules in a cell or tissue by binding to them with a fluorescent dye.

To treat some diseases: for cancer the monoclonal antibody can be bound to a radioactive substance, a toxic drug or a chemical which stops cells growing and dividing.

Cell division

Cell cycle

Interphase

Mitosis

Cytokinesis

Before a cell can divide it needs to grow and increase the number of sub-cellular structures such as ribosomes and mitochondria. The DNA replicates to form two copies of each chromosome.

In mitosis one set of chromosomes is pulled to each end of the cell and the nucleus divides.

Finally the cytoplasm and cell membrane divides to form two identical cells

Meristem tissue can differentiate into any type of plant cell throughout the life of the cell

Produce clones of plants quickly and economically.

Rare species can be cloned to protect from extinction.

Crop plants with special features such as disease resistance can be cloned to produce large numbers of identical plants for farmers.

RP6 -the effect of light on the rate of photosynthesis

Independent variable = Distance from the lamp (affects light intensity)


Dependent variable = Number of bubbles of oxygen


Control variables=

Brightness of lamp

Colour of the light

Concentration of sodium hydrogen carbonate

Temperature

Length of pondweed

Type / species of pondweed

Light intensity = 1/ Distance from light^2