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Principle of Pharmacology and Antibiotic Resistance …
Principle of Pharmacology and Antibiotic Resistance
By: Rania Gisella F.H (2306172464)
Drugs
Drug preparations used for therapy
Prophylactic drugs
Treatment drugs
Drug transport
Cellular Uptake, Distribution, Passive Diffusion, Active Transport, Blood Circulation
Various Drug Delivery
Nano-Drug Delivery Systems
Liposomes
Beaded Delivery Systems
Nanoparticulate Systems
Colloidal Drug Carriers
Drug selection principles
Maximising the effectiveness of drugs
Respecting patient choice
Minimize the costs
Prescribe within the limitations of our knowledge, skills and experience
Rational drug usage
Appropriate indication
Appropriate drug
Appropriate administration, dosage, and duration
Appropriate patient
Appropriate patient information
Appropriate evaluation
Special attentions
Pediatric, Geriatric, Pregnant women,
Patients with Renal Impairment -Allergies or sensitivities -Multiple Chronic Conditions -Taking multiple Medications (Polypharmacy) -Cognitive Impairment or Mental health conditions -Genetic Variations
Antibiotic Resistance
Genetic Mutation
Altered target sites
Horizontal Gene Transfer
Enzymatic Inactivation
Efflux pump
Biofilm Formation
Factors Influencing Drug Effects
Pharmacokinetics
Absorption
Bioavailability
Rate of absorption
Pharmacodynamics
Distribution
Rate of absorption
Tissue Accumulation
Drug-Receptor Interaction
Agonist/Antagonist ctivity
Drug-Enzyme Interaction