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LEISHMANIA DONOVANI - Coggle Diagram
LEISHMANIA DONOVANI
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DIAGNOSIS
Wet mount WBC count ( 3000 /μl) falls to 1000/μl Peripheral blood film Needle biopsy/aspiration Insect cell culture medium NNN- Novy McNeal Nicolle or Hockmeyer's medium
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INTRODUCTION
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It's an obligatory intracellular parasite Affects dogs, foxes, jackel
HABITAT: Reticuloendothelial system (spleen, liver, bone marrow, lymph nodes)
LIFE CYCLE 
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• Vertebrate host ( Man ,dog, rodents etc)
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TREATMENT
Hepatosplenomegaly Fever, Malasie , headache Leucopenia Emaciation
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• Chemotherapy: Amphotericin B, Monomycin, Pentamidine
It has 2 life forms
PROMASTIGOTE
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15-25 μm in length & 1.5-3.5 μm in breadth Axoneme extends outside as an "free flagellum" *The " free flagellum" is equal to the size of the body or similar to "undulating membrane"
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Anemic condition WBC gets less *Lymphadenopathy
Hepatosplenomegaly Fever, Malasie , headache Leucopenia Emaciation :