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Plasmodium - Coggle Diagram
Plasmodium
LIFE CYCLE
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If it is remained dormant
Relapsing condition ( sleeping sporozoites) remain dormant in liver . patients are carriers
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Mosquito uptake blood ( it has to take more than 12/ mm³of blood) then only mosquito will get the infection.
1 microgamete is sufficient for fertilization, after fertilization , it starts moves to midgut region, oocysts developed.
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Sporozoites rupture the cell and release and move to the buccal cavity ( salivary gland) of mosquito
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Infected mosquito bites the person, it release the sporozoites which infects the liver cells. Micro merozoites infect RBC and Macro merozoites infect liver cells.
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MORPHOLOGY
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SCHIZONTS - early, late ,mature
PRE ERYTHROCYTICSCHIZONTS - size 40μm× 80μm
It will have merozoites inside it.
No.of merozoites, it varies from10,000 to 50,000 in number
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PATHOGENESIS
3 different condition
1.Febrile paroxysms
- Anaemia.
- Spleenomegaly.
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Malariae ( 4 different types according to species)
1.Vivax malaria - Benign tertian malaria
2.falciparum malaria- Malignant tertian malaria
3.Malariae malaria - Quarant malaria
4.ovale malaria - Benign tertian malaria
Complications in P.falciparum
- Cerebral malaria
2.Algit malaria
- Septicemia
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LAB DIAGNOSIS
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Sample - blood
Microscopic - thin blood smear, Leishman and Giemsa staining
Serological test - ELISA , immunoprecipitation, indirect haemagglutination, complement fixation, immunofluorescence.
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