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Toxoplasma gondii - Coggle Diagram
Toxoplasma gondii
Morphology
Tachyzoites
Crescent shaped
Size - 15× 6 micrometer
Central nucleus - 1- 2 micrometer
Anterior end- Rhoptery ( parasite mouth)
Side depression - Cytostome
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Oocyst
Oval or round shaped
Contain double layer wall contains single spherical shape structure called sporoblast
Non infective
Becomes infective when it is present in the soil and develop sporozoites
Contains 8 sporozoites
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Sources of infection
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Pathogenicity
Congenital Toxoplasmosis
Post natal Toxoplasmosis
Brain damage
Jaundice
Eye damage
Blindness
Lymphadenopathy
Pnemonosis
Laboratory diagnosis
Sample - blood, sputum
Stain- Giemsa,PAS
Serology - indirect fluorescent agglutination test, ELISA
Molecular - PCR
Imaging- MRI, CT scan
Others - Animal inoculation, Skin test
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Life cycle
Enteric cycle (Cats)
Contaminated soil ( sporulated oocyst) or by taking meat ( Bradyzoites or Tachyzoites)
Bradyzoites enters into the tissue and then converted into Tachyzoites.
Multiply enormous
Sexual cycle it forms male and female gametes
Fertilized as zygote
Forms oocyst which is unsporulated
Soil it becomes sporulated ( 8 sporozoites)
Oocyst ingested into intermediate host
Exoenteric cycle
Taking the under cooked meat which contains Bradyzoites or food contains Oocyst
Oocyst - Bradyzoites (Excystation)
Bradyzoites starts infecting the tissue layer
Bradyzoites - Tachyzoites & infect the other organs
A symptomatic but it causes congenital transmission and causes secondary infection
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Obligate intracellular parasite
Opportunistic parasite
1st described in France in 1908 ( Nicolle and Manceaux)
Cat - definite host, humans or cattle- accidental host
Habitat - human beings reticulum endothelium system, cat- intestinal region
