Development of Body Cavities & Diaphragm

Mesoderm

Diaphragm Development

Body Cavity Partitioning

Body Cavity Formation


  1. Describe the development of lateral plate mesoderm, intra-embryonic coelom, cardiogenic mesoderm, and septum transversum
  1. Describe the derivatives of the different portions of the lateral plate mesoderm, cardiogenic mesoderm, and septum transversum

Lateral Plate Mesoderm

Splanchnic portion

Cardiogenic Mesoderm

Somatic

Septum Transversum

Embryonic Folding

  1. Assess the consequences of head, tail, and lateral folding
  1. Compare and contrast the body cavities in the adult and the initial body cavity that
    forms in the embryo

Head folding

  1. Analyze the formation of the initial intra-embryonic coelom prior to head folding

Tail Folding

  1. Assess the consequences of head folding on the overall shape of the intra-embryonic
    coelom and on the cranial loop specifically. What terms are utilized to describe the segments of the intra-embryonic coelom following head folding? What are the pericardioperitoneal canals related to?

Lateral Folding

  1. Assess the consequences of lateral folding especially within the peritoneal cavity and the overall shape of the intra-embryonic coelom
  1. Describe the linings of the intra-embryonic coelom. How do they compare to the adult?
  1. Assess how the septum transversum partitions the intra-embryonic coelom. Which portions are separated? Is this a complete separation? Which areas of the intra- embryonic coelom can still communicate with each other?
  1. Assess how the pleuropericardial folds partition the intra-embryonic coelom. Which portions are separated? Is this a complete separation? Which areas of the intra- embryonic coelom can still communicate with each other?
  1. Describe how expansion of the pericardioperitoneal canals ventrally contributes to the
    formation of the fibrous pericardium

Pleuropericardial folds

  1. Assess how the pleuroperitoneal membranes partition the intra-embryonic coelom. Which portions are separated? Is this a complete separation? Which areas of the intra- embryonic coelom can still communicate with each other?
  1. Describe the four sources that contribute to the formation of the diaphragm

Pleuroperitoneal membranes

Esophageal Mesentary

Septum Transversum

Lateral Body Wall

  1. Assess how the septum transversum is formed and how it contributes to the sources of
    diaphragm formation
  1. Assess the portion of the diaphragm that is initially completed by the pleuroperitoneal membrane. Why does the ratio of contribution from the pleuroperitoneal membrane to the diaphragm decrease?
  1. Analyze the contribution of the dorsal mesentery of the esophagus. Which portion(s) of
    the diaphragm develop from the dorsal mesentery of the esophagus?
  1. Assess the contribution from the lateral body wall. How does expansion of the pericardioperitoneal canals (pleural cavities) play a role in this contribution to the diaphragm and to the development of the costodiaphragmatic recesses?

Disorders of the Diaphragm


  1. Analyze the underlying cause of congenital diaphragmatic hernia, the most common
    location (and why), and the consequences of herniated abdominal contents within one of the pleural cavities