Development of Body Cavities & Diaphragm
Mesoderm
Diaphragm Development
Body Cavity Partitioning
Body Cavity Formation
- Describe the development of lateral plate mesoderm, intra-embryonic coelom, cardiogenic mesoderm, and septum transversum
- Describe the derivatives of the different portions of the lateral plate mesoderm, cardiogenic mesoderm, and septum transversum
Lateral Plate Mesoderm
Splanchnic portion
Cardiogenic Mesoderm
Somatic
Septum Transversum
Embryonic Folding
- Assess the consequences of head, tail, and lateral folding
- Compare and contrast the body cavities in the adult and the initial body cavity that
forms in the embryo
Head folding
- Analyze the formation of the initial intra-embryonic coelom prior to head folding
Tail Folding
- Assess the consequences of head folding on the overall shape of the intra-embryonic
coelom and on the cranial loop specifically. What terms are utilized to describe the segments of the intra-embryonic coelom following head folding? What are the pericardioperitoneal canals related to?
Lateral Folding
- Assess the consequences of lateral folding especially within the peritoneal cavity and the overall shape of the intra-embryonic coelom
- Describe the linings of the intra-embryonic coelom. How do they compare to the adult?
- Assess how the septum transversum partitions the intra-embryonic coelom. Which portions are separated? Is this a complete separation? Which areas of the intra- embryonic coelom can still communicate with each other?
- Assess how the pleuropericardial folds partition the intra-embryonic coelom. Which portions are separated? Is this a complete separation? Which areas of the intra- embryonic coelom can still communicate with each other?
- Describe how expansion of the pericardioperitoneal canals ventrally contributes to the
formation of the fibrous pericardium
Pleuropericardial folds
- Assess how the pleuroperitoneal membranes partition the intra-embryonic coelom. Which portions are separated? Is this a complete separation? Which areas of the intra- embryonic coelom can still communicate with each other?
- Describe the four sources that contribute to the formation of the diaphragm
Pleuroperitoneal membranes
Esophageal Mesentary
Septum Transversum
Lateral Body Wall
- Assess how the septum transversum is formed and how it contributes to the sources of
diaphragm formation
- Assess the portion of the diaphragm that is initially completed by the pleuroperitoneal membrane. Why does the ratio of contribution from the pleuroperitoneal membrane to the diaphragm decrease?
- Analyze the contribution of the dorsal mesentery of the esophagus. Which portion(s) of
the diaphragm develop from the dorsal mesentery of the esophagus?
- Assess the contribution from the lateral body wall. How does expansion of the pericardioperitoneal canals (pleural cavities) play a role in this contribution to the diaphragm and to the development of the costodiaphragmatic recesses?
Disorders of the Diaphragm
- Analyze the underlying cause of congenital diaphragmatic hernia, the most common
location (and why), and the consequences of herniated abdominal contents within one of the pleural cavities