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PATHOLOGY of PRGNANCY - Coggle Diagram
PATHOLOGY of PRGNANCY
ECTOPIC PREGNANCY
frequent recurrences (10-25%), maybe predisposition
diagnosis
- signs of pregnancy
- US
- "discriminatory" beta-hCG values
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risk factors
- PID
- chronic salpingitis
- tubaric adherences
- endometriosis
- leiomyoma
- previous pelvic surgery
- assisted fertilization procedures
evolution
hemorrhage (shock), spontaneous regression, tubaric abortion
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HYDATIFORM MOLE
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clinics:
- bleeding
- uterine enlargement
- increased bHCG levels >100,000 mlU/MI
forms
complete
- more frequent
- all villi involved
- diffuse trophoblastic hyperplasia
- diploid karyotype
- risk for choriocarcinoma development (16%)
partial
- rare
- few villi are involved
- focal trophoblastic hyperplasia
- karyotype 69XXY
- little-to-no-risk to develop choriocarcioma
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CHORIOCARCINOMA
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highly malignant, chemosensitive, 1/20,000 pregnancies
pathology
macro:
- soft
- yellowish
- necrosis
- hemorrhage
micro:
- highly atypical cells
- cytotrophoblast
- syncytiotrophoblast and intermediate trophoblast elements
- infiltrative
- atypical and numerous mitoses
- necrosis
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ECLAMPSIA
pre-eclampsia
- hypertension
- proteinuria
- edema
eclampsia
- convulsions
- cerebral edema
- cerebral hemorrhage
- pulmonary edema
- DIC
- cortical renal necrosis
- retinal detachment
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organs involved
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liver
HELLP syndrome
- Hemolysis
- Elevated Liver enzymes
- Low Platelets
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