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Lymphatic Sys.Mike Mendez P.2 - Coggle Diagram
Lymphatic Sys.Mike Mendez P.2
Major functions of the Lymphatic & Immune systems
Lymphatic System: collects and carries away excess tissue fluid from interstitial spaces and returns it into the blood.
Immune system: response by body against specific pathogens, their toxins or metabolic products also defends the body against infection and keeps track of pathogens.
Location of Lymphatic organs and their functions
Spleen Located in the upper left abdominal cavity.filter blood and removes damaged blood cells and bacteria.
Lymph nodes located in groups/chains along the lymphatic vessels.filter substances that travel through lymph fluids.
Thymus located in the chest above heart. shrinks in size as you get older. responsible for the maturation on immune cells.
Purpose and examples of First, Second and Third line of defense
First Line: Mechanical barriers like skin and mucous membranes.
Second line Defense: Chemical barriers, natural killer cells, inflammation, phagocytosis, and fever.
Third Line of Defense Response by the body against specific pathogens their toxins or metabolic wastes cellular immune response and humoral immune response.
Artificial vs. Naturally acquired immunity
Naturally acquired- injection of antiserum/gamma globulins
-short term immunity without simulating immune response
Artificially Acquired: due to exposure of vaccine containg weakened/dead cells
simulation of immune response without severe symptoms of disease.
Humoral response and cellular response
Cellular Immune Response- response through cell to cell contact as activated Tcells interact with antigen- bearing cells
Humoral Response- Antibodies travel through body fluids to attack & destroy antigens.
Antigens and antibodies
Antigens- any large molecule that can trigger an immune response.
Antibodies- protein produced by the immune system that detects substances, and antigens.
The body makes Self antigens before birth and immune response is directed against non self molecules.
Innate(natural) immune defenses and Adaptive(acquired) immune defenses
Innate Defenses Guard Against pathogens and responds quickly
Include mechanical and chemical barriers, inflammation, phagocytosis, natural killer cells, species resistance and fever
Adaptive defenses- responds against only specific types of pathogen, responds slower
helped by specialized lymphocytes, secrete antibodies.
Passive vs. Active immunity
Passive immunity- antibodies & memory B cells are produced
obtained through antigen exposure
Active immunity- no memory cells produced because there is no antigen contact & no immune response
-Obtained through antigen exposure
Cells involved in the immune system and their functions
Lymphocytes- attack viruses, bacteria, debris, & damaged cells
Tcells Destroy Pathogens
Macrophages- destroy Foreign particles, debris & damaged cells.
Bcells- Make Antibodies