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Schizophrenia Spectrum and Other Psychotic Disorders (Part 1 & 2) -…
Schizophrenia Spectrum and Other Psychotic Disorders (Part 1 & 2)
Psychological & Cultural Factors
Families and Relapse
Cannabis Use and Abuse
Diathesis-Stress Model
Stress
Origin of Schizophrenia
John Haslam (1764-1844)
Philippe Pinel (1745-1826)
Benedict Morel (1809-1873)
Emil Kraepelin (1856-1926)
Eugen Bleuler (1857-1939)
Genetic Influences
Twin Studies
Adoption Studies
Endophenotypes
Endophenotyping
Smooth-pursuit eye movement
Neurobiological Influences
Dopamine
Brain Structure
Prenatal (before birth) and Perinatal Influences
Rhesus (Rh) Incompatibility
Maternal Stress
Treatment of Schizophrenia
Electroconvulsive shock therapy
Biological Interventions
Antipsychotic Medications
Neuroleptics
First Generation Antipsychotics
Chlorpromazine (Thorazine)
Haloperidol (Haldol)
Second-Generation Antipsychotics
Clozapine (Clozaril)
Risperidone (Risperdal)
Olanzapine (Zyprexa)
Non-compliance to Medication
Extrapyramidal Symptoms
Akinesia
Tardive Dyskinesia
Additional Biological Treatment
Transcranial magnetic stimulation
Psychosocial Interventions
Token Economy
Cognitive Remediation
Behavioral Family Therapy
Vocational rehabilitation
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Clinical Description
Positive Syndrome
Distortion
Delusion
Delusion of Grandeur
Delusion of Persecution
Delusion of Reference
Hallucination
Negative Syndrome
Avolition
Alogia
Anhedonia
Asociality
Affective Flattening
Disorganized Symptoms
Disorganized Speech
Disorganized Behavior
Catatonia
Historic Schizophrenia Subtypes
Paranoid Schizophrenia
Disorganized Schizophrenia
Catatonic Schizophrenia
Schizoaffective Disorder
presence of either a major depressive or a manic mood episode concurrent with psychotic symptoms that meet schizophrenia
Delusions or hallucinations for 2 or more weeks in the absence of a major mood
episode (depressive or manic) during the lifetime duration of the illness.
Schizophreniform Disorder
Acute Schizophrenic Episodes
disorder lasts at least 1 month but less than 6 months.
Two (or more) of the following, each present for a significant portion of time during a 1-month period.
Delusion, Hallucination, Disorganized Speech, Grossly Disorganized, Negative Symptoms
Delusional Disorder
Two (or more) of the following, each present for a significant portion of time dur-
ing a 1-month period
Delusional Subtypes
Erotomanic
Grandiose
Jealous
Somatic
Substance-Induced Psychotic Disorder
This disorder has also presence of one or both of the delusion and hallucination
Psychotic Disorder Associated with Another Medical Condition
Should be prominent hallucination or delusions
There is an medical findings that the disturbance is the direct pathophysiological consequence of another medical condition
Brief Psychotic Disorder
Involves sudden onset of psychotic symptoms
Presence of one or more positive symptoms
Often precipitated by extremely stressful situations
Attenuated Psychosis Syndrome
Who start to develop psychotic symptoms
High-risk for having schizophrenia and may be at an early stage of the disorder