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Addison's disease - Coggle Diagram
Addison's disease
biochemistry
anemia
eosinophilia
lymphocytosis
hyperkalemia
azotemia
hyponatremia - low sodium level
Pathophysiology
sodium loss
prerenal azotemia
hypotension
dehydration
weakness
hyperkalemia
weakness
lethargy
anorexia
cortisol deficiency
همه علائم بالا + hypoglycemia
treatment
First: rapid correction of hypovolemia
lactated Ringer
normal saline
plasma lyte
hypoglycemia
IV dextrose
1:3
medications
Acuate
dexamethasone sodium phosphate
0.25 mg/kg IV First day
0.15 mg/kg second day
chronic
daily
prednisone 0.1 - 0.2 mg/kg PO
DOCP 2.2 mg/kg IM/SC monthly
initial dose for average sized cat 12.5 mg IM/SC
Range
cat
1-9 years
Dog
1 - 12 years
median : 4 years
Historical Findings
Dog
depression
weakness
hypovolemia
dehydration
collapse
hypothermia
melena
hairloss
painful abdomen
polyuria/ polydipsia
cat
like the dog except for hair loss and melena
DEFINITION
deficient production of glucocorticoids and mineralocorticoids