Please enable JavaScript.
Coggle requires JavaScript to display documents.
HOMEOSTATIC SET POINT : 5mM, therefore: beta cells make insulin in…
-
therefore: beta cells make insulin in advance and package them into vesicles to wait for a rise in glucose
GLYCOGENESIS
Binds to an insulin receptor found on the liver cells, activating signalling pathways for the activation of glycogen synthase
As the glucose gets used up, the amount of free glucose in the cell reduces so more glucose moves into cell by facilitated diffusion through the glucose transporter
THE MORE GLYCOGEN PRODUCES THE MORE GLUCOSE INTO THE LIVER CELLS
Glucose is turned into glycogen through glycogen synthase: which serves as an energy reserve for your body.
Muscle and fat cells have glucose transporters called GLUT4 but need INSULIN to work
insulin binds to receptor (allosterically changes the shape of an intercellular portion of the molecule) activating enzymatic activity → signals from the extracellular environment to intercellular environment
insulin receptor starts a chain reaction of enzymes inside the cell + the vesicle with GLUT4 moves to the plasma membrane and fuses
Glucose is transported into the muscle and fat cells
GLUCAGON binds to its receptor (glucose receptor) on the surface of liver cells and activates signalling pathways that refsult in the activation of an enzyme (GLYCOGEN PHOSPHORYLASE) which catalyses the breakdown of glycogen back into glucose