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Respiratory Medications - Coggle Diagram
Respiratory Medications
COPD
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Classification
- Severity of airflow limitation
GOLD Grades
- Assessment of exacerbation risk
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Combined Assessment
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- Number of exacerbations/year
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Aims of Treatment
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- Reduce risk and severity of excerbation
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Pharmalogical Treatment
- Initial Management of Stable COPD
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- Treatment of Exacerbations
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Bronchodilators
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- ↑ Activation of β2 receptors
- ↑ cAMP
- Relaxation
- ↓ Activation of M3 receptors
- ↓CA2+
- Relaxation
- PDE inhibitors - Theophylline
- Inhibition of PDE
- ↓ Degradation of cAMP
- ↑ cAMP
- Relaxation
- Leukotriene Pathway Inhibitors
- Inhibition of activation of CysLT1 receptors
- ↓ Ca2+
- Relaxation
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Inhaled Corticosteroids
MOA
Inhibition of infiltration of airways by ltmphocytes, eoisinophils, mast cells
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Definitions
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Asthma
Chronic inflammatory bronchial airway disease characterised by bronchial hyperreactivity and reversible airway obstruction
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