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Non-Retroviral Drugs, Blocks DNA polymerase and DNA chain elongation,…
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- Blocks DNA polymerase and DNA chain elongation
- Blocks DNA polymerase and chain elongation
- Directly bind to pyrophosphate binding site and block DNA polymerase
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- Oseltamivir (Tamliflu) → DOC for Swine flu and Bird flu
- Zanamivir
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- DOC for Hep B and D Coinfection
- MOA- Production of Viral RNA degrading enzymes
- Inhibits RNA dependent RNA Polymerase
- Direct Acting Antiviral
- Current treatment of choice for Hep C
- (eg. Sofosbuvir, Velpatasvir, Paritaprevir)