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Famous researchers - Coggle Diagram
Famous researchers
Alois Alzheimers
German psychiatrist and neuropathologist, born 1864
Mostly known for identifying the first published case of "presenile dementia" which later got the name Alzheimer's disease
Met the patient Auguste Deter, in 1901, who showed symptoms for memory loss, disorientation, and psychological changes, at the age of 51.
After she dies Alzheimer examined her brain and found abnormal clumps (amyloid plaques) and tangled bundles of fibers (neurofibrillary, or tau, tangles)
Jöns Jakob Berzelius
Swedish chemist, born 1779
He proposed that letters should be used to represent the elements and discovered several chemical elements such as: Selenium (Se) 1817, Silicon (Si) 1824, Thorium (Th) 1828, and Cerium (Ce) 1803
Berzelius introduced the term "protein" when he suggested the name from the Greek work "proteios" which means primary. This reflects his recognition of the substance as very important in living organisms.
Gerardus Mulder
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He concluded that the substance, now called protein, was high on nitrogen. He proposed that proteins were formed from the polymerisation of a basic unit, which pointed towards the macromolecular nature of proteins.
Alexander Fleming
Scottish bacteriologist, born 1881
Received the Nobel prize for the discovery of Penicillin, the first broadly effective antibiotic
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Kai Linderstrom-Lang
Danish biochemist and enzyme scientist, born 1896
Known for his studies on the structure, function, and dynamics of proteins and enzymes
He was one of the pioneers in the study of protein structure, emphasizing the importance of understanding the three-dimensional structure of proteins for comprehending their function.
He conducted pioneering studies on hydrogen exchange in proteins, which provided insights into protein folding and the stability of protein structures.
John Kendrew
British biochemist and crystallographer, born 1917
Groundbreaking contributions to the understanding of the structure of proteins by determining the three-dimensional structure of the protein myoglobin
This discovery gave him, together with Max Perutz, the Nobel prize in 1962
This provided the first visual evidence of how protein's amino acid sequence folds into a specific three-dimensional structure to perform its biological function.
Cyrus Levinthal
American molecular biologist, born 1922
He is known for his contributions to the understanding of DNS and protein folding. One of his most notable contributions to science is the formulation of the "Levinthal's paradox", which is a thought experiment that highlights the complexity of protein folding.
He addressed the question of how proteins fold so quickly into their native three-dimensional structures despite the large number of possible conformations. He said that the folding would take much longer time if the case was that proteins fold randomly. He therefore proposed that the folding of proteins is highly ordered and an efficient process, guided by the protein's amino acid sequence and the physical and chemical properties of its environment.
Rudolf Virchow
German physician, pathologist, biologist, and politician, born 1821
He first coined the term "amyloid". This was before it was known that amyloids are proteins. He named the structures he found amyloid after "amylum" (starch) and "eidos" (like) which reflects Virchow's initial characterization of these deposits as starch-like.
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