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giant cell - Coggle Diagram
giant cell
predileksi
proximal tibia
distal femur
distal radius
proximal radius
pulmonary metastase
1-2 %
diagnosis
x ray
lytic lesion pada epiphyseal extend ke epihysis distal
chest radiography
chest CT
lab
CBC, ESR, CRP, ALP, LDH
bone scan
CT scan dan MRI
T1
LOW to intermediate intensity
homogen
t2
HETEROGEN
epidemiology
found in mature skeleteon
20-45 tahun
female> male
miicroscopic
gross pathology
gritty, gray to tan brown
multinucleated giant cell
banyak sel di dalamnhya
di luarnya terdapat mononuclear cwll yg dikelinig spindle
differential diagnosis
brown tumor
permah operasi tiroid ga
non ossifying fibroma
secondary maligannt GCT
setelah diradioterapi
treatment
non oeprative
inoperable
bisphosphonate
operative
extensive curettage and reconstruction
filling defect
pake cement atau bone graft
advantage of bone graft
advantage of boen cement
thermal effect
enbloc
total excision of tumor
indication
extensive stage 3 tumors
intraarticular pathological fracture
amputation
anamnesis
nyeri
history
clinical feature
limiting joint movement
pathological fracture
physical exam
swelling
tenderness
classification
campanacaii
grade 2
cortex thinning
grade 3
grade 1
well defined margin
enneking
etiology
fusi dari proliferating mononuclear cell
complication
recurrence rate