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Purpuras - Coggle Diagram

- - - - Peripheral
        
        Excess of destruction
        
        Allo-immune
        
        Post-transfusion, placental
        
        Autoimmune
        
        Acute ITP
        
        Children+elderly
        
        Lupus,Evans,RA
        
        Immuno-allergic
        
        Viral infection(HIV,HCV,CMV,EF,Flu)
        
        Helicobacter pylori
        
        Drug intake
        
        Excess of consumption
        
        Thrombotic thrombocytopenic purpura
        
        Microangiopathic Hemolytic anemia+Neuro disorders+Thrombocytopenia
        
        Disseminated intravascular coagulation (DIC)
        
        low platelet count, a prolonged partial thromboplastin time, a prolonged
        prothrombin time, and elevated levels of D-dimer and fibrin degradation products.
        
        Thrombotic microangiopathies
        
        Hemolytic uremic syndrome HUS +Thrombotic thrombocytopenic purpura
        
        Purpura fulminans
        
        Sequestration
        
        Portal HTN, Sarcoidosis...
      - Platelet production(Central)
        
        Defieciencies: folate ,B12,iron....
        
        Renal failure
        
        Idiopathic aplastic anemia
        
        Neoplasia: Leukemia, lymphoma....
        
        Toxicity: Alcohol
  - - - Non inflammatory
        
        Embolic
        
        Fat embolism
        
        Vascular fragility
        
        Senile purpura
        
        Thrombotic
        
        Antiphospholipid Sd+ DIC
      - Inflammatory
        
        Hypersensitivity vasculitis
        
        Infection
        
        Toxic (Pesticides)
        
        Drugs
        
        Secondary systemic vasculitis
        
        CTD (SLE, Sjogren,RA...)
        
        Malignancy
        
        Cryoglobulinemia
        
        Hyperglobulinemic Waldenström Purpura
        
        Primary Systemic vasculitis
        
        Essential cryoglobulinemia vasculitis
        
        ANCA
        
        GPA
        
        EGPA
        
        Rheumatoid purpura