PANS & SANS
Parasympathetic Nervous System
(Rest & Digest)
Sympathetic Nervous System
(Fight or Flight)
Funtions
Funcitons
activates the fight or flight response
takes over in stressful situations
mainly comes out of the thoracic & lumbar regions of the spinal cord
activates the rest and digest response
activates when the body is at peace
mainly originates in the brain
Symptoms
pupil constriction
increased saliva
activates & increases digestion
normal heart rate and/or (bradycardia)
Symptoms
pupil dilation
decreased saliva
rapid heart rate
HBP
Ganglia
SHORT preganglionic neurons & LONG post ganglionic neurons
acetylcholine = pre ganglionic neurotransmitters
norepinephrine = post ganglionic neurotransmitters
Drugs
Sympathomimetic (adrenergic agonist)
increases sympathetic response
mimics the sympathetic nervous system
happens when the PNS is too restful
Ex of what sympathomimetic drugs do: Dopamine : Increase BP ; Norepinephrine : Increase BP ; Epinephrine : Bronchodilation
Sympatholytic (adrenergic antagonists)
blocks sympathetic response
mimics the PNS
used when SNS is in overdrive
Ex of what sympatholytic drugs do: Drugs are used to treat high BP, anxiety : lower heart rate
Ganglia
Acetylcholine = pre ganglionic neurotransmitter
Cholinergic = post ganglionic neurotransmitter
Drugs
Parasympathomimetic (cholinergic drugs)
Parasympatholytic (anticholinergic drugs)
Examples of what Parasympathomimetic drugs do:
Pyridostigimine
Pilocapine to treat xerostomia
Examples of what parasympatholytic drugs do:
Ipratropium : Bronchodilation
Atropine : Increase heart rate, dilate pupils
Drugs that are used to mimic the sympathetic nervous system when the body is too restful.
Blocks parasympathetic response
Drugs that mimic the parasympathetic nervous system
used when the sympathetic nervous system is in overdrive.
click to edit