Please enable JavaScript.
Coggle requires JavaScript to display documents.
Isospora belli, Screenshot_2024_0303_200137 - Coggle Diagram
Isospora belli
Life cycle
2 cycles ;
√ Asexual - Merogony
√ Sexual - Gametogony
⬇
Intake of Contaminated food or water containing cyst ( Asexual cycle starts)
⬇
8 sporozoites released ➡ intestine after attachment .
⬇
Sporozoites starts invading intestinal epithelial region ( transforms morphological diff).
⬇
Starts to multiply & forms Merozoites ➡ these trophozoite forms have active motility with " Cilia".
⬇
Transformation ➡ In ' Upper Intestine'
⬇
( Sexual cycle starts )
Takes place in ' Small intestine '
⬇
Fertilization takes place ➡ " Microgamete - 20-25" & Macrogamete only "One ".
Only 1 microgamete fertilize macrogamete.
⬇
Zygote forms ↔ " Immature Oocyst " ➡ Sporozoite.
⤵
This forms into Mature Sporozoite .
-
-
-
Discovery
- By " Virchow" in '1860' but named by "Wenyan" in '1923'
- Mostly found in African & South American country.
-
Morphology
- Single form - Oocyst
- " Ellipsoidal " shape
- 20-30 × 10-19 micrometer ( l × b)
- 2 forms " Immature & Mature stage "
- 1st formed Oocyst contains "2 Sporoblast" called "Immature double layered ".
- It forms Sporocyst inside it forms "4 sporozoite".
- Sporocyst size - 9-14 × 7-12 micrometer ( l × b).
- The mature cyst has Sporozoite is the infective form of human .
Pathogenesis
PATHOGENESIS :I. belli can cause marked villous atrophy, and crypt hyperplasia in the small intestine. Inflammatory infiltrates in the lamina propria include eosinophils, neutrophils, lymphocytes and plasma cells. 
.
-
-
-