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ISOSPORA BELLI, Introduction, IMG_20231226_192900, IMG_20231226_192736,…
ISOSPORA BELLI
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It is a coccidian parasite which can cause diarrhea
in humans.
It discovered d by Virchow in 1860 but
named in 1923 by wenyen
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Distribution
African,south American
Countries
Morphology
Single form-oocyst
Elipsoidal shape or
elongated oval shape
Size 20-3010-19
Each oocyst is surrounded by a
thin smooth two-layered
Immature oocysts seen in the
feces of patients con tain
two sporoblasts.
The oocysts mature outside the body
Two sporoblasts result in form sporocyst
Inside sporocyst develop 4 sporozoites
Size of sporozoites 9-147-12
Pathogenesis
Mostly assymtopmatic
Immunocompetent- mild diarrhoea
Resolve back in 5-6 weeks
without any treatment
Immunocompromised -general complications
Major complications - respiratory infection
Lympadenopathy,splenomegaly
Lab diagnosis
Sample: stool
Wet mount, iodine solution
Acid fast staining &
fluroscence staining
Stool concentration method
Molecular method -PCR,ELISA
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