Isospora belli
Introduction
First Discovered By
1.Vinchow 1860
Named By
2.Wenyen 1923
Isospora also affect the large & Small intestine. It is have oocyst (infective form)
Immature cyst is having only sporoblast (Single Layer)
Mature eyst is having Sporocyst (Double
Walled with 4 sporozoite)
Morphology
Oocysts :
size - 20 to 30m x 10-19 µm
(Infective form) Sporocyst Size 9-14 x 7- 12 micro meter.
Shape - Elipsoildal
Two sporoblasts
Two sporocysts, each containing four sausage-shaped Sporozoites
Life Cycle
Lab Diagnosis
Clinical Symptoms
Asymptomatic - A number of infected
individuals remain asymptomatic.
Mild gastrointestinal discomfort to
severe dysentery
Pathogenesis
Treatment
Combination of trimethoprim and sulfamethoxazole
Co - Trimoxazole
Prevention and Control
Proper personal hygiene
Adequate sanitation practices
Sexual
Asexual
Stool examination (Microscopic)
Wet mount
Iodine Solution
Mordified Acid fast staining -
Fluroscent staining - Rodamine dye
Auramine dye
Stool concentration methods - Zinc sulphate, formalin solutions
Molecular method
PCR, ELISA
Gametogony
Merogony
