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Rotavirus - Coggle Diagram
Rotavirus
The characters
DS non-enveloped RNA
Multiple in cytoplasm
Because it's has
RNA
Ether and chloroform resistance
Due to
Non-enveloped
Has 6 serotypes
Major cause of infantile gastroenteritis
Pathogenesis & immunity
commonly in children between 6 months to 2 years.
The virus multiplies in the villi of the small intestine
Leading to
impaired Na and glucose (absorption)
Causing
watery non bloody diarrhea,
vomiting, fever
and abdominal pain.
Dehydration, acidosis
and shock and death occur if not treated
Diagnosis
Demonstration of viral antigen
By
Elisa
Latex agglutination
IF
Virus detection
By
Immuno-electron microscope
Searching for specific nucleic acid
By
PCR
Immunity
IgA In the intestine
protects against
Reinfection
Colostrum IgA
Protect
newborns up the age of 6 months
Vaccines
Rota teq
Monovalent
Rotarix
Pentavalent
They are live attenuated
The taken orally
Mode of transmission
Faeco-oral
Treatment and control
Correct the loss of water and electrolytes
By
Replacement of them