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ULCERATIVE, VESICULAR AND BULLOUS LESIONS - Coggle Diagram

- - - - Recurrent oral & genital ulcers, ocular lesions,
        skin involvement, neurological symptoms.
    - - Multidisciplinary approach, systemic corticosteroids, immunosuppressive drugs.
    - - Chronic autoimmune disease.
        Triad: Oral ulcers, genital ulcers, eye lesions.
  - - - CF
        
        Larger, deeper ulcers, systemic reactions, misdiagnosed as malignant.
      - TTT
        
        Systemic steroids, antibiotics, immunosuppressants.
      - DEF
        
        Recurring large, deep, irregular bleeding ulcers on non-keratinized mucosa.
    - - CF
        
        Rapid onset, tiny ulcers, frequent recurrence.
      - TTT
        
        Topical/systemic steroids, antivirals, immune modulators.
      - DEF
        
        Recurring tiny pinhead multiple ulcers, rapid healing.
    - - CF
        
        Prodromal features, round, shallow ulcers, no scarring.
      - TTT
        
        Topical steroids, supportive measures, tetracycline mouthwash.
      - DEF
        
        Recurring small, shallow, painful ulcers on non-keratinized mucosa.
- - - - Oral mucosa involvement, bullae formation, scarring, conjunctiva involvement.
    - - Topical/intralesional steroids, dapsone, azathioprine, cyclophosphamide.
    - - Chronic autoimmune disease.
        Autoantibodies against basement membrane.
  - - - Fragile bullae, oral mucosa involvement,
        Nikolsky’s sign positive.
    - - Systemic corticosteroids, topical corticosteroids, immunosuppressive drugs.
    - - Chronic autoimmune disease.
        Autoantibodies against desmoglein 1 & 3.
- - - - Recurrent intra oral herpes
        
        CF
        
        Recurring vesicles, ulcers, usually less severe than primary.
        
        TTT
        
        Antivirals, Symptomatic relief.
        
        DEF
        
        Recurrent HSV1 infection in the oral region
      - Herpes labialis .
        
        CF
        
        Cold sores, vesicles, ulcers, often triggered by stress or sunlight.
        
        TTT
        
        Antivirals, Topical treatments.
        
        DEF
        
        HSV1 infection around the lips
      - Primary herpetic gingivostomatitis
        
        CF
        
        Prodromal symptoms, fever, inflamed gingiva, vesicles, ulcers.
        
        DEF
        
        Initial HSV1 infection, oral lesions
        
        TTT
        
        Supportive care, Topical anesthesia, Antivirals.
    - - Hand foot and mouth disease
        
        CF
        
        Fever, sore throat, oral ulcers, skin rash on hands and feet.
        
        TTT
        
        Supportive care, Pain relief.
        
        DEF
        
        Coxsackie virus, oral and skin lesions
      - Acute lymphonodular pharyngitis
        
        CF
        
        Fever, sore throat, small gray-white papules in posterior pharynx.
        
        TTT
        
        Supportive care, Pain relief.
        
        DEF
        
        Coxsackie virus, throat inflammation
      - Herpangina
        
        CF
        
        Fever, sore throat, dysphagia, vesicles, ulcers.
        
        DEF
        
        Coxsackie virus A, oral lesions
        
        TTT
        
        Supportive care, Proper hydration.
  - - - Acute onset, target lesions, mucous membrane involvement.
    - - Supportive, topical steroids, antivirals, systemic steroids (moderate-severe).
    - - Acute, self-limited skin condition. Immune complex hypersensitivity.
    - - CF
        
        Sudden onset, vesiculo-bullous skin lesions, ocular complications.
      - TTT
        
        Medical emergency, withdrawal of causative agent, supportive care, systemic steroids.
      - DEF
        
        Severe mucocutaneous-ocular syndrome.
        Triad: Skin, eye, urogenital lesions.
    - - CF
        
        Similar to SJS but more severe, extensive skin detachment.
      - TTT
        
        Medical emergency, withdrawal of causative agent, supportive care, systemic steroids.
      - DEF
        
        Severe form of SJS; extensive skin sloughing.