Cryptosporidium parvum
Morphology
Cyst 4-5um diameter
Double walled electron layer
4 crescent shaped sporozoites
Nucleus
Anterior pointed and posterior rounded
Life cycle
Sexual
Asexual
Injestion of cyst by contaminated food
Gastric juice breaks double walled and sporozoites are released
They attach to intestine and transform to trophozoite
Type 1 meronts
Type 2 meronts
8 merozoite
4 merozoites
Microgamont
Macrogamont
12-17 microgametes
1 microgametes
Zygote
Zygote
Pathogenesis
Immunocompetent
Immunodeficiency
Cholera like illness
Respiratory crytosporidois
Cholecystitis
Respiratory crytosporidois
Diarrhoea
Lab diagnosis
Wet mount
Stool concentration technique
Modified acid fast staining
Immunofluorescence antibody
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Histopathological examination
Elisa pcr
Treatment
Spiramycin
Azithromycin
Reduce dehydration
Stop immunosuppressants drug
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