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Cryptosporidium parvum, Screenshot_20231221-170810, Screenshot_20231221…
Cryptosporidium parvum
Morphology
- Only one form - cyst known as Oocyst.
- Oval or spherical in shape.
- Double wall cyst covering - 2 electron dense layer.
- Inside cyst, 4 crescent shaped sporozoites.
- Infective form.
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Pathogenesis
Immunocompetatnt - short term, self limiting diarrhea
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Immunocompromised - prolonged, life threatening, cholera- like illness
Gastrointestinal diseases, respiratory Cryptosoridiosis, cholecystis
Lab test
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Concentration techniques : * zinc sulfate floatation
- Formalin ether sedimentation
Modified Acid fast staining
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Molecular examination
- PCR
- ELISA
Treatment
- Immumocompetent - treatment to prevent dehydration
- Individuals recieving immunosuppressant drugs - cessation of immunosuppressants.
- AIDS or congenital deficiency - continuous supportive therapy.
- Antimicrobial agents - spiramycin, azithromycin
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