Trichomonas vaginalis
Morphology
Single morphology - Trophozoite
Pear shaped
Anterior end has four flagella
One flagellum Runs along the side of the body called as undulating membrane
Jerky locomotory
Axostyle is extended from the body like sharp pointed knife
Tears the vaginal portion of host and enter into host
Life cycle
After it enter into the habitat ,they starts multiply by binary fission
Trophozoite in vagina gets excreted through urine
Pathogenicity
Incubation period 4 - 28 days
Vaginal pH of more than 4.5 facilities infection
Binding to the vaginal epithelium by various metabolic enzymes
2 condition
Acute
Chronic
Vulvovaginitis
Colpitis malcularis
dysuria and lower abdominal pain
Discharge may be frothy and yellowish green color
Undulating membrane supported by a rod like structure called costa
Pruritis and pain during coitus
Vaginal discharge is scanty, mixed with mucus
Complications
Pyosalpinx , endometriosis , infertility, low birth rate
Sometimes respiratory distress
Association of increased HIV transmission and cervical dysplasia
Lab diagnosis
Microscopy - wet count (jerky motility)
Samples - vaginal ,urethral discharge, urine sediment
Giemsa stain
Acridine orange fluorescent stain
Direct fluorescent ab test
Culture
Trussell and Johnson
Cysteine peptone liver yeast maltose media
Treatment
Metronidazole
Clotrimazole