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Adrenergic antagonists - Coggle Diagram
Adrenergic antagonists
Selective a1 antagonists
Mainly anti-hypertensive by blocking a1 receptors therefore blocking action of NE, E on alpha receptors on the blood vessels (no vasoconstriction)
Lowering blood pressure.
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Mainly antagonist of a1a adrenergic receptor, by releaxing muscles in prostate and bladder making it easier to urinate
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(First Generation) Non selective b antagonist, N-alkys groups are isopropyl, tert butyl
Propranolol 
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Non selective a/b
Labetalol
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Carvedilol
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Selective b1 antagonists
(Second generation)
4-subsituted arlyoxypropanolamines are Selective b1 blockers, N-alkyl groups are isopropyl, tert butyl.
Esmolol, shorter duration (have ester)
Metaprolol longer duration (no ester)
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