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Pharmacology - Coggle Diagram
Pharmacology
Pharmacodynamics
Main goals of drugs
3 ways drugs interact with the body
Receptors
Types
Bounds with drugs
Cell signaling
Drug specificity VS selectivity
2 types of ligands
Physiological antagonism
Invers antagonists
Factors influencing drug concentration needed for effect
Potency
Effects of drugs on organism
Adverse reactions
Types of toxicity
Idiosyncrasy
Medecine hypersensitivity
Mutagenicity
Iatrogenic diseases
Repeated administration
Association of drugs
Parameters changing pharmakodynamics effects
Dose
Types
By effect
By administration schedule
By quantity
Difference with dosage
Factors changing dose
Introduction
Toxin
Branches of pharmacology
Drug/active substance
Difference with a meidcal product
Type
Based on toxicity
Based on prescription and manufacture
Source
Administration
3 phases of the drug after administration
Ways of administration
2 systematic ways
10 local ways
Pros and cons
4 ways of absorption (through digestive system)
Influence of food int he GI tract
Pharmacokinetics
Steps
Ditribution
Structure of capillaries
Brain/blood barrier
Placental barrier
Metabolism
Definition
Where and why ?
Phases
2 different types of enzymes
Products
Factors affecting metabolisation
Excretion
Where ?
In animals with liver or hepatic pb
Phases of urine formation ?
Absorption
Different ways
Factors influencing absorption
Drug related
Body related
Changing speed
Delaying absorption
Speeding absorption
Bioavailability
First-pass effect
Parameters
Plasma concentration graph
Apparent volume
Bioavailability
Clearance of drug
Half-life
Bioequivalence