Please enable JavaScript.
Coggle requires JavaScript to display documents.
Obesity and metabolic syndrome - Coggle Diagram
Obesity and metabolic syndrome
Obesity
BMI over 30
Trends
Over time, obesity is going up
Causes
A lack of leptin
Leptin is a hormone that gives the feeling of being full
Insulin secretion and efficacy differences
Very unbalanced calorie intake and burning
Adipogenesis/energy-lipid metabolism differences
Regulating body weight
The hypothalamus is involved in thirst and hunger
Hormones come from fatty tissues signaling the amount of fat tissue
Hormones come from the stomach which signal the presence of food
Hormones come from the pancreas signalling glucose presence and break down of food
Damage to the hypothalamus is known to affect bodyweight
It can affect appetite and feedback systems
Issues with obesity
leads to cardiovascular disease
Heart attack
Causes hypertension
Causes diabetes mellitus
Causes infertility and hirsutism
Causes arthritis and gout
linked to some cancers
Endometrium
Colon
Breast
Ovary
Gallbladder
Causes gallstones
Causes incontinence
Causes varicose veins
Causes breathlessness and sleep apnoea
Causes fatty liver disease
Types of obesity
Central visceral obesity
High risk
Blood passes through fatty tissues in the central cavity and moves to the liver
Blood holds fat which can effect liver function
Fat can even get into the liver
Fatty blood can affect muscle function
Adipose tissues produce a variety of hormones which impact the body
Cytokines
Can create insulin resistance
Fatty acids
Increase chance of diabetes
Subcutaneous gynecoid obesity
Low risk
Therapies
Low level
Exercise
Diet
Treat cardiovascular risk factors
Low mid level
Supervised low calorie diet
high level
Surgery
bariatric surgery
Involves changing the structure of the stomach
Gastric banding
Vertical banded gastroplasty
Gastric bypass
Mid level
Drugs