Please enable JavaScript.
Coggle requires JavaScript to display documents.
Biochemical markers of CVD - Coggle Diagram
Biochemical markers of CVD
Heart disease
issue with blood and oxygen supply to heart muscle
Can result in myocardial infarction
Where part of the heart muscle dies
Acute myocardial infarction
Loss of blood
Ischaemia
Necrosis
Caused by atherosclerosis
Diagnosis
Characteristic ECG changes
Markers in blood of heart muscle damage
Sever crushing chest pain
Myocardial infarction is defined by troponin over the 99th percentile of reference population
Risk stratification
Biochemical markers
Primary prevention
Aims to identify those who need preventative treatment
People can be assessed using assign score
Biochemical markers that signal risk
LDL cholesterol
Lipoprotein A
Total cholesterol
Troponin
CRP
Biochemical markers that signal decreased risk
HDL cholesterol
Heart Failure
Impairment of heart function
Blood pools in the wrong parts of the body because of dysfunctional pumping
Diagnosis
Imaging to analyse the heart structure
ECG
Biochemical markers
BNP
BNP is useful but isn't very specific
Biochemical markers of myocardial damage
Troponin
Cardiac specific variations
Can measure with immunoassays giving relatively cardiac specific results
Hospitals tend to measure troponin I or T more than C
Found in the thin filaments of striated muscle complexed to actin
Troponin can indicate heart damage from a tiny section of damaged tissue