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Lymphoid Tissue - Coggle Diagram
Lymphoid Tissue
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Definition
Lymphoid tissue encompasses organs like the spleen, thymus, and lymph nodes, along with diffuse lymphocyte aggregations.
Lymph, a clear fluid, flows through lymphatic vessels, tissues, and red bone marrow.
It originates from capillary filtration of interstitial fluid and eventually drains into venous blood, serving roles in immune responses, dietary lipid transport, and interstitial fluid drainage.
Primary Lymphatic Organs
Thymus
The thymus, located in the superior mediastinum behind the sternum, is a primary lymphoid organ active in childhood but atrophies from puberty onward.
It consists of two lobes with cortex (cellular, dark staining) and medulla (less cellular, light staining).
The thymus is crucial for the development of immunocompetent T-cells, proliferation of mature T-cell clones, immunological self-tolerance, and secretion of hormones (thymosin, thymulin, thymopoietin) by reticular epithelial cells in the cortex.
Definition
Primary lymphatic organs, crucial for lymphocyte formation and maturation, include the red bone marrow and the thymus gland.
Both B- and T-cells originate in the bone marrow, while B-cells mature there as well. In contrast, T-cells migrate to the thymus for maturation.