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Intro to Virology - Coggle Diagram
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Non enveloped viruses
Stable- Resistant to temp., acid, proteases, detergents. Survive stomach/gut spread by faecal oral route
Enveloped Viruses
Unstable- Sensitive to acid, proteases, drying. Cannot survive the stomach/gut spread by blood, resp. droplets
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Shingles
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Rash, viral latency in nerve tissue
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Acute Infection: Rapid onset of symptoms,
clear virus by immune system,
death (Ebola)
Chronic Infection: latent (clinically silent in immunocompetent pt.)
Persistent production of virus with varying degrees of disease
Electron Microscope
Advantages: Global detection of all virus present, good for unknown infections
Disadvantages: low sensitivity, time consuming, experienced staff
Serology
Advantages: fast, amenable to automation & large no. of samples, high sensitivity
Disadvantages: availability of kits, not always specific, not good for unknown diseases, complicated interpretation of response
Antigen Detection
Advantages: specific identification of virus, rapid, cheap
Disadvantages: no good for unknown infectious agents, low sensitivity
Virus Isolation
Advantages: viable infectious virus, unknown infectious agents, provides enough sample for further characterization
Disadvantages: time consuming, requires expertise, quality of sample