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Physiology of Pregnancy - Coggle Diagram

- - - - Maturation that sperm must undergo, increased flagellar beat, accelerated motility pattern, plasma membrane are more fragile
      - Acrosomal Reaction
        
        Zona pellucida can bind many sperm but only 1 fertilizes the egg, sperm releases
        
        Blocks Once sperm penetrates Perivitelline Membrane
        
        Fast Block: Depolarization
        
        Slow Block: Release of cortical granules and zona "hardening"
- - - - Zygote
        
        Early Cleavage 4-cell stage
        
        Morula
        
        Early Blastocyst
        
        Late Blastocyst
        
        2 cell Lineages
        
        2 more items...
        
        Fluid Filled central cavity: Blastocoel
        
        Implantation very invasive - Conceptus digests into uterine endometrium and becomes completely surrounded by endometrial tissue
    - - Ovulated follicle has formed a corpus luteum secreting both Progesterone and estrogen , sustains endometrium and stimulates secretory activity
      - Conceptus signals presence to mother or CL wil self destruct (hCG maintains CL)
      - Decidual Reaction
        
        Proliferation, enlargement, differentiation of endometrial stromal cells occurs, caused by prolonged exposure to estrogen and progesterone, implanation and spreads throughout uterus
- - - - 6th week (end): embry 22-24 mm long, head v large compared to trunk, fingers and toes present, external ears as elevations
        
        8th week end: Embryo almost 4 cm, all major organ systems, few new structures after this
- - - - Fetal: Develops from chorionic tissue
      - Maternal: Derived from endometrium
  - - - Hormones
        
        HcG
        
        Present in maternal serum 8th day aftetr fertilization, and maintains production of progesterone by CL
        
        hCS
        
        Human placental lactogen
        
        Stimulates breast development, supports fetal bone growth, makes glucose availbale to fetus
        
        Estrogen
        
        Initially from CL then from placental later
        
        Intiaially estrone, then estriol
        
        Maintains uterine endometrium, contributes to breast development
        
        Progesterone
        
        Initially from CL and grandually assumed by placenta
        
        Relaxing effect on smooth muscles (uterus, blood vessels, urinary system, GE sphincter, intestines)